TREXAVIVE is a subcutaneous therapy designed to treat major depressive disorder and treatment resistant depression. It works by targeting both GABA and opioid pathways – offering a dualmechanism approach that is fast-acting, non dissociative, and non-sedating.
Now funded by the Department of Veterans’ Affairs (DVA) for eligible patients.
EXPLORE USE CASES BELOW
For Healthcare Professionals
Clinical Use - Indications:
MDD, TRD
Dual-mechanism:
GABAergic + opioid modulation
Delivery:
Subcutaneous injection
Safety Profile:
No sedation – No dissociation – No addiction liability
What is TREXAVIVE? A new treatment designed to help when others haven’t. It targets key brain systems involved in depression, without the side effects often seen in traditional medications.
What to do next? Ask your doctor or psychiatrist about TREXAVIVE – You may be eligible if you’re living with major depression, or treatment resistant depression.
TREXAVIVE is Trexapharm’s lead therapy – a purpose-built, repurposed intervention for high-need mental health conditions. Already approved for use with DVA funding, its trajectory reflects our broader platform opportunity.